>
The
Wobenzym Story
> What
are Enzymes?
> Functions
of Wobenzym
> Benefits
of Wobenzym
> Technology
& Entrepreneurism
> Tech
Development
>
100 tablets $19.95 reg price $36.75
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>
200 tablets $35.41 reg price $55.00
Millions of people take Wobenzym every day for
one simple reason: they feel better!
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here to order
>
400 tablets $64.97 reg price $119.70
This anti-aging supplement has gained a "cult
following" among physicians and consumers alike
click
here to order
>
800 tablets Clear $109.95 reg price $224.95
Millions of people take Wobenzym every day for
one simple reason: they feel better!
click
here to order
The
Wobenzym Story
by Aftab Ahmed, Ph.D.
The story of
enzymes is as fascinating in its details as it is amazing in
its applications in promoting human health and wellbeing.
Enzymes are proteins that are an integral part of Nature. In
fact, life without enzymes would not be possible. Enzymes
are needed for each and every chemical reaction that make
life possible. No vitamin, mineral or hormone can exert its
beneficial effects in the human body without the involvement
of enzymes. Despite their central role in all bodily
functions, it is only now that the full import of enzymes in
human health and disease has begun to be fully appreciated.
MUCOS Pharma, the pioneer in systemic enzyme therapy, has
been the standard bearer for the last fifty years in having
paved the way to elucidate the function of enzymes, and
their use as an oral systemic therapy.
The history of enzyme research reads quite like a detective
story, as diligence of dedicated scientists tested the
secrets of enzyme function and developed preparations to
alleviate human pain and suffering. It all started with a
simple question: What are the enzymes? Years, even decades,
of work finally yielded insights into the architecture of
enzymes, which is beguiling in its simplicity and elegance,
yet embodies the intricacies of their function.
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What
Are Enzymes?
Enzymes are
proteins composed of amino acids, the basic building blocks
of life, arranged in chains that spontaneously fold into
three-dimensional structures. These three-dimensional
structures confer specificity of function. Whereas all
enzymes are proteins, not all proteins are enzymes. Enzymes
are involved in nearly all metabolic and physiological
processes in the body. Thus, they are a key in the
maintenance of a strong immune system, a robust
cardiovascular tree, a healthy and intact central nervous
system, and optimal hormonal balance in the body.
The body produces its own supply of enzymes in requisite
amounts, as and when they are needed. The enzymes, however,
do get "used up" at rates faster than the body can
replenish its supplies under a variety of conditions, such
as consumption of "junk" foods or intake of
medicines. In fact, with advancing years, the body loses its
ability to produce sufficient amounts of enzymes to keep up
the demands of the body imposed by metabolic attrition. This
insufficiency is the root cause of susceptibility to chronic
and age-related diseases.
Given that enzymes are required in all cells of the body to
assist in chemical reactions, they participate in a myriad
of reactions that allow organs, tissues and glands to
function optimally and thrive. If the body is imagined as an
efficient chemical factory, it is the enzymes that fuel each
and every reaction in that factory. As such, enzymes
function as catalysts. That is, they make things work at a
faster rate. The reason enzymes are needed for bodily
functions is that, in their absence, most of the
physiological processes would either not take place, or
would proceed at an excruciatingly slow speed. In other
words, at normal body temperatures, it will be virtually
impossible for the cells to perform their tasks speedily and
efficiently. That means that enzymes initiate, maintain,
accelerate, and terminate biochemical processes in the body
to foster health and vitality.
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Functions
of Enzymes
Since they have
unique structure, each enzyme is meant to carry out a
specific task. Any given enzyme is evolved to fulfill a
definite function, and this specificity allows the body to
strictly control the use of enzymes. Once activated, an
enzyme will perform its specific function until it is
"exhausted," or it is inhibited by another enzyme,
in which case its activity is curtailed and/or stopped. As
researchers have found out after years of painstaking and
laborious work, there is a good reason for this control: It
prevents bodily processes from spinning out of control,
which may be deleterious to health and wellbeing.
Even casually, the specificity of enzymes suggests that
there will be particular types. In fact, Nature has
"engineered" families of enzymes for specific
tasks. One of the most beneficial and abundant classes of
enzymes is referred to as proteolytic enzymes. Enzymes in
this category have the ability to "nibble" at
other proteins, and break them down into smaller chains of
amino acids. Hence the name, proteolytic enzymes, which
literally means "chewing up proteins."
On the surface, it might appear counterintuitive to degrade
proteins in the body. Are proteins not required for optimal
cellular function, and do they not afford good health and
vibrancy well into the golden years? Indeed, they do! In
disease, however, the human body produces proteins that
could potentially have injurious effects, and further
compromise health if left unattended. It was precisely this
goal that Drs. Max Wolf and Helen Benitez set themselves
roughly one-half a century ago when they started their quest
to find a wholesome, effective and safe alternative for
human health and wellbeing. Of course, their objective was
to understand how c comes about and whether natural
alternatives could be designed that will not wreak havoc on
the human body as radiation and chemotherapy do. Despite
their scientific astuteness, little did Drs. Wolf and
Benitez anticipate that their systemic enzymes will afford
man immense health benefits, irrespective of whether or not
systemic enzymes "cured" c.
Drs. Wolf and Benitez, along with Dr. Karl Ransberger, a
young biomedical researcher from Germany, tested a large
number of enzymes from animal and plant sources. The work
was slow, and it progressed in fits and starts, since the
researchers had to optimize the conditions to isolate and
purify the enzymes. Not only that, they had to struggle to
maintain the activity of the enzymes, because the enzymes
are notorious for being finicky and unstable. That is, if
the enzymes are not handled properly under precisely defined
condition, they become inactive. After all, the researchers
were working in the 1950s, a time when the basic enzyme
technology was still in its infancy, and individual
scientists had to rely more on their wits than technology to
tweak answers from Nature.
Once Drs. Wolf and Benitez had optimized the conditions
necessary to maintain the enzyme activity, they started the
next part of their work to combine and evaluate various
enzyme formulations in assessing their beneficial effects.
These must have been trying times for Drs. Wolf and Benitez.
By its very nature, the work was slow, and required almost
superhuman patience. After years of dedicated work, they
finally experienced the Eureka effect! Their systemic
enzymes worked! Perhaps, better than they thought, since
beneficial effects of their enzymes were far more varied
than they had expected in their wildest expectations.
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Benefits
of Wobenzym
Why did Wobenzym
work so well? To a large extent, the answer rests with the
type of enzymes contained in Wobenezym. These are
proteolytic enzymes, which cleave other proteins. While
under normal physiological condition, proteolytic enzymes
maintain homeostasis in the healthy body, they also break
down aberrant proteins that may arise during various
diseases. Thus, in basic research and several tens of
clinical studies carried out over the years under the
auspices of MUCOS Pharma, Wobenzym has been found to
degrade, for example, harmful and abnormal immune complexes
that precipitate autoimmune diseases. Furthermore, immune
complexes also thicken the blood, which potentially could
trigger an array of diseases. These studies are a matter of
public domain, and may be readily retrieved.
In fact, after some 50 years of Dr. Wolf's work, we have
come full circle. Dr. Wolf started his research to find a
cure for c. After decades of diligent work, almost
remarkable determination and scientific insights,
proteolytic enzymes have been shown to help c patients.
Thus, Wobe-Mugos, a sister product to MUCOS' flagship
product Wobenzym, is under consideration by the United
States FDA for Orphan Drug status as adjuvant therapy for
multiple myeloma, which is the c of B cells in the
blood. In addition, Dr. Nicholas Gonzalez, affiliated with
Cornell University Medical School in New York, has worked
tirelessly to show that proteolytic enzymes are effective in
the clinical management of pancreatic c. In recognition
of his painstaking work, Dr. Gonzalez has been awarded a
research grant by the National C Institute to carry out
a clinical trial. Undoubtedly, the work of scores of
scientists and physicians over the decades deserves
recognition, which has made this sea change possible. By the
same token, however, it is also a testament to the insights,
vision, and belief that Dr. Wolf had in his work.
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Technology
and Entrepreneurism
The story of
science is replete with coincidences, which make things turn
for the better. Dr. Karl Ransberger's association with Drs.
Wolf and Benitez was one such event that ushered in the era
of systemic enzyme therapy. In addition to being an
accomplished researcher, Dr. Ransberger also had an
entrepreneurial streak, which he used to make systemic
enzyme the world's premier preparation, and maintains even
today to chart new trails in enzyme therapy. Professional
association between Dr. Ransberger and his mentor Dr. Wolf
soon develop into business partnership and life-long
friendship. When Drs. Ransberger and Wolf decided to move
back to Germany with this truly innovative enzyme
preparation for its time, in recognition of the work by Drs.
Wolf and Benitez, it was given the name WoBeEnzym.. Over the
past 45 years, Wobenzym has become a household name in
Germany in particular but also in other European countries
as well. Furthermore, Wobenzym is recognized all over the
world with MUCOS Pharma's subsidiaries in countries such as
Argentina, Mexico, Spain, Czech Republic, India, Pakistan,
Korea, New Zealand and, of course, the United States.
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Technology
Development
Before this
success became possible, numerous scientific and technical
challenges had to be met and overcome. One of the major
challenges was to preserve the integrity of the enzymes
during the manufacturing process. Enzymes are notoriously
fragile: Exposure to heat deactivates them. In addition,
even the slightest exposure to moisture prods them to
chewing themselves up. That is the nature of the beasts.
Enzymes contained in Wobenzym are proteins, and proteolytic
enzymes do break themselves down (auto-proteolysis) -- quite
like the snake that cannibalizes itself by chewing on its
own tail.
That was the challenge that faced Dr. Ransberger in the
early 1960s: Namely, how to stabilize the enzymes while
purifying them in large quantities with the highest potency.
Purity and potency of enzymes is absolutely necessary to be
effective. Dr. Ransberger was at the forefront of the
efforts to develop the technology to achieve these goals.
Under his leadership, scientists and researchers developed
techniques that ensured that the enzymes are purified to the
highest possible degree and are stabilized such that their
biological activity is retained.
The next challenge, of course, was to the manufacturing of
enzymes in the tablet form. Making tablets during the
manufacturing process generates considerable heat. Being
heat-sensitive as the enzymes are, it was absolutely
necessary to keep the temperature down in order for enzymes
to remain active. With remarkable ingenuity, Dr. Ransberger
and his team optimized manufacturing conditions to cool down
the tableting machinery and equipment to maintain exactly
the correct temperatures throughout the manufacturing
process for enzymes to remain "alive" and
biologically active.
Like his mentor Dr. Wolf, the driving force for Dr.
Ransberger's hard work, dedication and commitment was to
help people. That is the reason, the innovations at MUCOS
did not stop in the 1960s. For example, today, MUCOS Pharma
isolates chymotrypsin, one of the enzymes in Wobenzym, by
state-of-the-art column chromatography. Over the years,
breakthrough thinking combined with a burning desire to find
safe and wholesome healthcare solutions has been the
hallmark of MUCOS' mission. It is the result of Dr.
Ransberger's lifelong focus, scientific and technological
expertise and a businessman's acumen that today Wobenzym is
world's most-renowned enzyme preparation.
By persistent efforts, extensive research and development,
and innovative technology, Dr. Ransberger found a way to
stabilize enzymes to withstand the harsh processing during
manufacturing. It is this patented technology that MUCOS
Pharma uses to not only extract enzymes from their sources
but also to stabilize them such that enzymes retain their
full biological activity. Without maximal activity, an
enzyme preparation is not what it is cut out to be. That is
the reason, MUCOS Pharma, and its North American corporate
partner, Marlyn Nutraceuticals, stands foursquare behind
Wobenzym.
Enzymes facilitate the smooth commerce of the bodily
functions. They are an indispensable part of human health
and disease. For good reason, then, in 1966, the editor of
the Scottish Medical Journal editorialized thus in 1966:
"Probably nearly half of our daily production of
protein in the body consists of enzymes. Indeed, each of us,
as with all living organisms, could be regarded as an
orderly succession of enzymatic reactions."
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>
100 tablets $15.95 reg price $35.00
click
here to order
>
200 tablets $26.95 reg price $51.50
Millions of people take Wobenzym every day for
one simple reason: they feel better!
click
here to order
>
400 tablets $57.35 reg price $114.00
This anti-aging supplement has gained a "cult
following" among physicians and consumers alike
click
here to order
>
800 tablets Clear $89.99, Red $99.95 reg price $199.95
Millions of people take Wobenzym every day for one
simple reason: they feel better!
click
here to order
|
