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Aging & Immune Function

The immune system helps repair a person's DNA. It also helps prevent infections caused by fungus, bacteria, viruses and other organisms. Immune system functioning changes with age.

The immune system's job is to seek out and destroy invaders that can harm the body. The ability of the immune system to fight infections declines with age. This does not mean that people necessarily get sick more often. But, as they get older, the risk of illness increases. As the immune system fails, elderly people are subject to infections, cancer, autoimmune disorders, or disorders directed against the body's own tissue, and to many chronic diseases. This may be due to the natural course of these diseases. Many diseases develop slowly and symptoms do not show up until later in life.

With age, many of the disease-fighting cells, called T-cells, or T lymphocytes, lose the ability to function. The body retains the same number of T-cells as before, but these cells are less able to control illness than the cells were in earlier years. Another function of the immune system is to produce antibodies to ward off foreign invaders in the body, such as bacteria and viruses. These antibodies produced by the immune system are a type of protein called immunoglobulins. As people age, their immune systems produce smaller quantities of antibodies. This means that vaccinations such as flu shots may provide less protection than when a person was younger. Another problem is that the body can lose its ability to distinguish what is foreign and what is part of itself. When this occurs, it can lead to autoimmune disease. It also means that the immune system cannot identify and fight cancerous, or malignant cells. This is one of the reasons that the risk of many cancers increases with age.

Finally, people lose nerve endings and skin cells with age. This increases the risk of injury. Cuts or openings in the skin allow bacteria to enter the body. Fighting off infection further taxes the immune system, creating a vicious cycle.

To minimize the risk of infection and individuals should:

  • keep vaccinations up to date. Individuals should receive a pneumovax immunization to prevent pneumonia. They should also be immunized against hepatitis, have flu shot every year, and get a tetanus shot every 10 years.
  • exercise daily and eat a well balanced diet
  • stop smoking.
  • minimize alcohol use.
  • get plenty of rest.
  • maintain an active lifestyle
  • implement home safety measures to reduce the chance of injury.

Reprinted with permission from HealthAnswers.com.

 

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