Supports Healthy Intestinal Flora.* - 1.26 Billion Intestinal Probiotics per Caplet.***

PRODUCT IS A SYNERGYSTIC MIXTURE OF
Fructooligosaccharides, Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus bulgaricus, Tumeric.

PRODUCT DISCUSSION
PhysioLogics’ BioFlora® provides a unique combination of prebiotic fructooligosaccharides and probiotic bacteria to support digestive function and promote healthy intestinal flora. Each caplet provides 1.26 X 109 intestinal probiotics at time of manufacture.*

STRUCTURE AND FUNCTION
The human gastrointestinal (GI) tract contains approximately 1014 bacterial cells comprised of more than 400 species. Because some of the bacteria are beneficial and others pose dangers to the body, it is extremely important to maintain a healthy balance of intestinal flora. Nutrition and the amount and type of fermentable material in the gut all influence the intestinal microbial ecology.*

Fructooligosaccharides are non-digestible short-chain carbohydrates that selectively promote the growth and activity of commensal bacteria in the gut. The resultant increase in bacterial cell mass enlarges bowel content and supports peristalsis of the alimentary tract. Fermentation of fructooligosaccharides results in the production of beneficial short-chain fatty acids like butyrate, the preferred substrate for energy generation by colonic cells.*

Probiotics are symbiotic microorganisms that, when ingested, exhibit positive influences on the health and physiology of the host. In addition to nutrient support during fermentation, probiotics can promote the digestibility of certain dietary nutrients. Lactobacillus acidophilus, naturally found in foods such as yogurt, releases many enzymes into the intestinal lumen which may support the bioavailability of proteins and fats. Lactases produced by lactic acid bacteria are delivered to the stomach and intestines, which may aid in lactose digestion.*

L. acidophilus can help establish a healthy GI flora composition through a variety of mechanisms, including competition for nutrients and attachment sites, promoting acidic pH, and production of hydrogen peroxide and bacteriocins. L. acidophilus is a normal constituent of the vaginal flora, where it contributes to the maintenance of a healthy acidic environment.*

INDICATIONS
Probiotics are commensal food supplements that improve the microbial composition of the intestines and aid in digestion of nutrients. Because it is believed that most probiotics are not permanently attached to the intestinal wall, daily consumption of these bacteria may help maintain a supportive level. In addition, antibiotics and certain regularly prescribed drugs may cause probiotic depletions. Supplementing your clients’ diets with BioFlora® may be desirable to promote gastrointestinal health by ensuring a daily supply of beneficial probiotics.*

HOW CLIENTS MAY BENEFIT

• Promote balanced intestinal and vaginal flora environments for healthy function.*
• Supports digestion and a favorable balance of intestinal flora.*
• Provides a combination of three exceptional probiotic strains.*

SUMMARY
Probiotics are live commensal food supplements that support the microbial composition of the intestines, aiding in the digestion of nutrients. PhysioLogics’ BioFlora® provides symbiotic lactic acid bacteria and fermentable Fructooligosaccharides for those who want to receive a daily supply of probiotics to maintain healthy intestinal flora.*

SUGGESTED DOSAGE
For adults, take one (1) caplet up to three times per day on an empty stomach or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you take with your health care providers.

REFERENCES
De Simone C, Ciardi A, Grassi A, Lambert Gardini S, Tzantzoglou S, Trinchieri V, Moretti S, Jirillo E. Effect of Bifidobacterium bifidum and Lactobacillus acidophilus on gut mucosa and peripheral blood B lymphocytes. Immunopharmacol Immunotoxicol. 1992;14(1-2):331-40.

Kopp-Hoolihan L. Prophylactic and therapeutic uses of probiotics: a review.J Am Diet Assoc. 2001 Feb;101(2):229-38

Marteau P, Flourie B, Pochart P, Chastang C, Desjeux JF, Rambaud JC. Effect of the microbial lactase (EC 3.2.1.23) activity in yoghurt on the intestinal absorption of lactose: an in vivo study in lactase-deficient humans. Br J Nutr. 1990 Jul;64(1):71-9.

Marteau PR, de Vrese M, Cellier CJ, Schrezenmeir J. Protection from gastrointestinal diseases with the use of probiotics. Am J Clin Nutr. 2001 Feb;73(2 Suppl):430S-436S.

Motta L, Blancato G, Scornavacca G, De Luca M, Vasquez E, Gismondo MR, Lo Bue A, Chisari G. [Study on the activity of a therapeutic bacterial combination in intestinal motility disorders in the aged] Clin Ter. 1991 Jul 15;138(1):27-35.

Murray, M. Probiotics. In: Encyclopedia of Nutritional Supplements. Prima Publishing, 1996, 44: 359-364.

= Vegetarian Formula