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From Classical Texts: The King of Kashi than asks the
critical question : "Oh! Lord, what are these factors whose wholesome and
unwholesome combinations are responsible for the growth of living beings and
their diseases?" Atreya said, "wholesome causes the growth of living
beings and unwholesome food the growth of disease."
WORLD AYURVEDA CONGRESS AT KOCHI,
KERALA ,INDIA
Introduction of Ayurveda (New Series) PrakritiThe word Prakriti means "nature" or natural form of the build and constitution of the human body. Pra means beginning and kriti means `to form¹. Life begins with the fusion of male gamete (shukra) and female gamete (shonita). When the male gamete and female gamete fuse the zygote carries the constitution (Prakriti) of the parents. At the time of fusion, the dominant Prakriti or the dosha predominant forms the characteristic constitution or prakriti of the individual. Doshaj Prakriti
Vataj individual have thin, lean and underdeveloped body structure. The dryness is manifested in hair, skin, nails and lips. Due to roughness and lightness the sleep is light and less. Due to the chal guna (mobile) the individual has a lot of early initiative in work but due to the khar guna (dryness quality) he gets tired because of loss of strength. Their memory is short but they are able to grasp quickly. The natural desires and craving for food and environment are opposite to the qualities of Vata. In the dreams such individuals see themselves flying, running and scared. They have low voice but are talkative. They are quick in thinking but indecisive. Such individuals are anxious and fearful. Their strength is less and has short life span. Pittaj Prakriti Pittaj individuals are thin and average built. The skin is glowing and more prone to freckles or moles. They have very good digestion and appetite. The sleep is irregular and in dreams they see fighting, violence, glowing objects and encounters with fire. They possess soft and scanty hair. Due to tikshana guna (sharpness) they have sharp memory and are intelligent in thinking. They are unable to bear even minimum heat. Such individuals get easily provoked and get very soon angry. They are argumentive. Their strength is medium and life span is medium. Kaphaj Prakriti Kaphaj individuals have well-built and steady body. Due to the snighda guna (unctuousness) Kaphaj individuals possess unctuous and oily skin and hair. The kaphaj individuals are slow in their activities but they have strong perseverance and are emotionally very mild. They posses steady and slow body movements. The seet guna (coldness) results in poor appetite and digestion. They have deep and slow voice and are silent and calm. In their dreams they visit the places having water, romantic places and usually see aquatic birds. Their sleep is deep. Their grasping power is slow but once if they learn, they regain it for longer time. Such individuals have mild emotions and are dull, steady in every aspect of life. They have maximum strength and their life span is long. Dwandaj Prakriti Such individuals possess the qualities of two prakritis. They can be: vataj-pittaj, pittaj-kaphaj or vattaj-kaphaj. Next Week: Manasika prakriti Vaidya Swaran Kaur (BAMS),
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Problem of the month: (through e-mail counselling)
Question :
Withanolides - much talked natural product
Ashwagandha (Withania somnifera) is a reputed
drug of Ayurveda. It finds application in Ayurvedic formulation for impotency
and arthritis. Withania somnifera is an erect evergreen shrub that grows to
about 1.5 meters in height in drier regions of India.It has been used for as
sedative, diuretic and anti-inflammatory properties agent Modern studies have
thrown light on immunomodulatory and anti carcinogenic activity of the plant and
it has been rightly called as 'Indian ginseng'.
Withania somnifera contains alkaloids and a special group of compounds called
withanolides, which are considered to be the active principles of the drug.
Chemically, withanolides are a group of naturally occurring oxygenated ergostane
type steroids having lactone in side chain and 2-en-1-one system in ring A. The
withanolides are present in the whole of the plant, but maximum presence have
been recorded from the leaves. Withaferin-A is the important withanolide
isolated so far.
Withaferin- A has shown potent tumor-inhibiting activity in Ehrlich ascites
carcinoma, Sarcoma 180, Sarcoma Black (SBL), and E 0771 mammary adenocarcinoma
in animal models. Besides it, Withaferin-A has significant anti-arthritic and
anti-inflammatory activities. Other withanolides have demonstrated immuno-modulator,
cardio-vascular and antifungal activity. 3-B-hydroxy, 2-3 dihydrowithanolide has
a significant protective effect in rats against carbon tetrachloride induced
hepatic damage.
The standardization of Withania somnifera is based on withanolide content and
the drug should contain 1.5% w/w of withanolide. Withanolides are present in
other members of Solaneace like Physalis minima, Nicandra physaloides, Physalis
philadelphica, Solanum torvum, Datura innoxia and Datura metel L.The
withanolides present in other plant include Withametelin, withacoagin, coagulin,
and withasomidienone, 3-dihydro-3-methoxywithaphysacarpin (1), and two known
compounds, withaphysacarpin, 24,25-dihydrowithanolide D, Withanicandrin,
Withaphysalin- A and Withaphysalin -B.
References :
1. Tripathi, A.K. Shukla, Y.N. & Kumar, S.
(1996). Ashwagandha (Withania somnifera): a status report 1996î J.Med Arom
Plant Sci; 18:46 -52.
2. Asthana, R and Raina, M.K., (1989). Pharmacology of Withania somnifera- a
review. Ind. Drugs; 26: 1-7.
3. Subhir, S. et-al., (1978). Pharmacological investigation on the leaves of
Withania somnifera. Ind. J. Pharmacol; 17:44-52.
4. Antitumor and radiosensitizing effects of Withania somnifera (Ashwagandha) on
a transplantable mouse tumor, Sarcoma-180. In: Indian J Exp Biol (1993 Jul)
31(7): 607-11.
5. Gupta, A. P., R. K. Verma, et al. (1996). Quantitative determination of
withaferin. A in different plant parts of Withania somnifera by TLC
densitometry. Journal of Medicinal and Aromatic Plant Sciences 18(4): 788-790.
{a} Central Inst. Med. Aromatic Plants, Lucknow 226 015, India.
6. Ziauddin, M., N. Phansalkar, et al. (1996). Studies on the immunomodulatory
effects of Ashwagandha. Journal of Ethnopharmacology 50(2): 69-76. {a}
Interdisciplinary School Health Sciences, University Pune, Pune 411 007, India.
Author: Dr Amrit Pal Singh, MD (Alternative
Medicine), Medical Executive, Ind -Swift Ltd Super Speciality Divison.
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(This is a short version, You are requested to contact author for detailed articles, Editor)
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THIS IS A HOUSE MAGAZINE FROM Dr. PRERAK SHAH, "PRERAK – The Holistic Medical Center". All details, thoughts shared in this bulletin are only for information purpose. We do not claim for any authenticity of the matter. We do not take any responsibility for any matter published here.